GSK2973980A is a potent and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor with an IC50 of 3 nM.

Product information

CAS Number: 2219321-25-0

Molecular Weight: 534.43

Formula: C25H19F5N4O4

Chemical Name: 2-[(2S)-6-(5-{[(3,4-difluorophenyl)carbamoyl]amino}pyrazin-2-yl)-1-oxo-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid

Smiles: OC(=O)C[C@]1(CC(F)(F)F)CCC2=CC(=CC=C2C1=O)C1=CN=C(C=N1)NC(=O)NC1=CC(F)=C(F)C=C1

InChiKey: OTKTZEZTFCAULO-DEOSSOPVSA-N

InChi: InChI=1S/C25H19F5N4O4/c26-17-4-2-15(8-18(17)27)33-23(38)34-20-11-31-19(10-32-20)14-1-3-16-13(7-14)5-6-24(22(16)37,9-21(35)36)12-25(28,29)30/h1-4,7-8,10-11H,5-6,9,12H2,(H,35,36)(H2,32,33,34,38)/t24-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.