SLUG rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20633-50, ES20633-100

Citations, Manuals and MSDS Available upon request.

Background: snail family transcriptional repressor 2 (SNAI2) Homo sapiens This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],

Alternate Name: SNAI2; SLUG; SLUGH; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2

Source: Rabbit

Applications: WB; IHC; IF

Dilution: WB: 1:500-1000 IHC: 1:200-500

Reactivity: Human; Mouse; Rat

Immunogen: Recombinant Protein of SLUG

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 30kD

Human Gene ID: 6591

Human SWISS Prot NO: O43623

Subcellular Location: Nucleus. Cytoplasm. Observed in discrete foci in interphase nuclei. These nuclear foci do not overlap with the nucleoli, the SP100 and the HP1 heterochromatin or the coiled body, suggesting SNAI2 is associated with active transcription or active splicing regions.

Research Use Only