SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm).

Product information

CAS Number: 1418275-26-9

Molecular Weight: 472.61

Formula: C27H28N2O4Si

Chemical Name: 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5, 5-dimethyl-3, 5-dihydrodibenzo[b, e]silin-10-yl)benzoate

Smiles: CN(C)C1=CC2=C(C=C1)C(C1=CC(=CC=C1C([O-])=O)C(O)=O)=C1C=CC(C=C1[Si]2(C)C)=[N+](C)C

InChiKey: YKWRGLWUKFMLBP-UHFFFAOYSA-N

InChi: InChI=1S/C27H28N2O4Si/c1-28(2)17-8-11-20-23(14-17)34(5,6)24-15-18(29(3)4)9-12-21(24)25(20)22-13-16(26(30)31)7-10-19(22)27(32)33/h7-15H,1-6H3,(H-,30,31,32,33)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

SiR-COOH could be used to conjugated inhibitors such as UNC2025 (Mer inhibitor). SiR-COOH is especially useful for small-molecule probes: it exhibits bright photostable fluorescence at near-infrared wavelengths, which are ideal for imaging deep through tissue; fluorescence is robust across physiological environments with little toxicity; it is amenable to super-resolution microscopy; and it exhibits an optimal degree of hydrophilicity for live-cell imaging.

Products are for research use only. Not for human use.