PGR Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22105-60, E-AB-22105-120, E-AB-22105-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PR

Target Synonym: NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB; PRGR; Progesterone receptor; Progestin receptor form A; Progestin receptor form B

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Mouse, Rat

Application: IHC-p, IF

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:1A5

UNIProt ID: P06401

Background: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: IHC 1:100-1:300, IF 1:100-200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only